Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 16/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826296 | 0.73 | NISCH (0.55) | NISCHADRA1AADRA1DADRA1B | |
| SCHEMBL11631748 | 0.70 | NISCH (0.54) | NISCH | |
| SCHEMBL12917958 | 0.69 | NISCH (0.53) | NISCHADRA1AHTR1D | |
| SCHEMBL722595 | 0.68 | CYP2A6 (0.56) | NISCHCYP2A6CYP2E1CYP3A4CYP2D6 | |
| SCHEMBL8832471 | 0.67 | NISCH (1.00) | NISCHADRA1AADRA1DADRA1B | |
| SCHEMBL1626317 | 0.67 | NISCH (1.00) | NISCH | |
| SCHEMBL3742115 | 0.66 | NISCH (0.56) | NISCH | |
| SCHEMBL22476609 | 0.66 | NISCH (0.55) | NISCHHTR1D | |
| SCHEMBL1886692 | 0.66 | NISCH (1.00) | NISCHADRA1AHTR1D | |
| SCHEMBL5476725 | 0.65 | NISCH (0.79) | NISCHADRA1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341213-B1 | 5-Aryl-substituted-2,3-dihydro-imidazo [1,2-a]furo[3,2-c]- or thieno[2,3-c]pyridines | SANDOZ AG (CH) | 1995-02-22 | — | — | EP | disclosed |
| EP-0341213-A2 | 5-Aryl-substituted-2,3-dihydro-imidazo [1,2-a]furo[3,2-c]- or thieno[2,3-c]pyridines | SANDOZ AG (CH) | 1989-11-08 | — | — | EP | disclosed |