Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460708 | 0.83 | DRD1 (0.49) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL9455644 | 0.83 | SRC (0.46) | DRD1ALDH1A1KMT2AGAA | |
| SCHEMBL2557247 | 0.81 | ALDH1A3 (0.63) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL7037791 | 0.80 | ATM (0.47) | ALDH1A1KMT2APPARGPPARACYP1A2 | |
| SCHEMBL3979786 | 0.79 | LDHA (0.59) | ALDH1A1KMT2APPARGPPARACYP1A2 | |
| SCHEMBL16753082 | 0.79 | LDHA (0.42) | KMT2APARP10PPARGPPARACYP1A2 | |
| SCHEMBL28871353 | 0.79 | SMN1; SMN2 (0.50) | ALDH1A1KMT2A | |
| SCHEMBL657468 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KMT2APARP10MMP1MMP2 | |
| SCHEMBL14922155 | 0.77 | ALDH1A3 (0.58) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL1811263 | 0.77 | ALDH1A3 (0.63) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871998-B2 | Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity | ASTRAZENECA AB (SE) | 2011-01-18 | — | — | US | disclosed |