Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520899 | 0.95 | CYP3A4 (0.44) | NR1I2CYP3A4CYP2D6L3MBTL1MAOA | |
| SCHEMBL9523124 | 0.95 | CYP3A4 (0.44) | NR1I2CYP3A4CYP2D6L3MBTL1MAOA | |
| SCHEMBL9521176 | 0.87 | L3MBTL1 (0.39) | NR1I2CYP3A4CYP2D6L3MBTL1AOC3 | |
| SCHEMBL9520450 | 0.86 | ACACB (0.46) | NR1I2CYP3A4CYP2D6L3MBTL1S1PR1 | |
| SCHEMBL8138473 | 0.84 | NR1I2 (0.66) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8666649 | 0.83 | CYP3A4 (0.46) | NR1I2CYP3A4CYP2D6L3MBTL1MAOA | |
| SCHEMBL8129872 | 0.83 | CYP2D6 (0.41) | NR1I2CYP3A4CYP2D6L3MBTL1MAOA | |
| SCHEMBL8670645 | 0.82 | CYP3A4 (0.48) | NR1I2CYP3A4CYP2D6L3MBTL1MAOA | |
| SCHEMBL16086028 | 0.81 | CYP3A4 (0.46) | NR1I2CYP3A4CYP2D6L3MBTL1MAOA | |
| SCHEMBL9522122 | 0.80 | AOC3 (0.50) | NR1I2L3MBTL1MAOAMAOBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |
| US-5175178-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |