Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201638 | 0.87 | NR1I2 (0.46) | L3MBTL1TDP1MAPTTSHRNR1I2 | |
| SCHEMBL9520899 | 0.82 | CYP3A4 (0.44) | L3MBTL1TDP1MAPTTSHRNR1I2 | |
| SCHEMBL9523124 | 0.82 | CYP3A4 (0.44) | L3MBTL1TDP1MAPTTSHRNR1I2 | |
| SCHEMBL9522122 | 0.78 | AOC3 (0.50) | L3MBTL1TDP1MAPTTSHRNR1I2 | |
| SCHEMBL9210194 | 0.76 | NR1I2 (0.53) | L3MBTL1TDP1MAPTTSHRNPY1R | |
| SCHEMBL9520450 | 0.74 | ACACB (0.46) | L3MBTL1TDP1MAPTTSHRNPY1R | |
| SCHEMBL9520566 | 0.74 | NR1I2 (0.44) | L3MBTL1TDP1MAPTTSHRNPY1R | |
| SCHEMBL8138473 | 0.72 | NR1I2 (0.66) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL9522035 | 0.72 | MAPT (0.35) | L3MBTL1TDP1MAPTTSHRCYP3A4 | |
| SCHEMBL9521646 | 0.72 | S1PR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |