SCHEMBL9520899

SCHEMBL9520899

C#CCCCCCOc1c(C)cc(-c2noc(C)n2)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
NR1I2 O75469 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.39
MAOB P27338 4/20 0.36
MAOA P21397 3/20 0.36
AOC3 Q16853 2/20 0.33
SCARB1 Q8WTV0 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9523124 1.00 CYP3A4 (0.44) CYP3A4CYP2D6NR1I2L3MBTL1MAOB
SCHEMBL9201638 0.95 NR1I2 (0.46) CYP3A4CYP2D6NR1I2L3MBTL1MAOB
SCHEMBL8138077 0.85 NR1I2 (0.64) CYP3A4CYP2D6NR1I2
SCHEMBL9521176 0.82 L3MBTL1 (0.39) CYP3A4CYP2D6NR1I2L3MBTL1AOC3
SCHEMBL9520450 0.81 ACACB (0.46) CYP3A4CYP2D6NR1I2L3MBTL1S1PR1
SCHEMBL8666649 0.81 CYP3A4 (0.46) CYP3A4CYP2D6NR1I2L3MBTL1MAOB
SCHEMBL8670645 0.80 CYP3A4 (0.48) CYP3A4CYP2D6NR1I2L3MBTL1MAOB
SCHEMBL8138473 0.80 NR1I2 (0.66) CYP3A4CYP2D6NR1I2
SCHEMBL8129872 0.79 CYP2D6 (0.41) CYP3A4CYP2D6NR1I2L3MBTL1MAOB
SCHEMBL16086028 0.79 CYP3A4 (0.46) CYP3A4CYP2D6NR1I2L3MBTL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523803-A1 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents STERLING WINTHROP INC. (US) 1993-01-20 EP disclosed
US-5175177-A 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS STERLING DRUG INC. (US) 1992-12-29 US disclosed