Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204440 | 0.90 | NR1H4 (0.35) | NR1H4MEN1KMT2APOLBAPEX1 | |
| SCHEMBL10757454 | 0.84 | CASP6 (0.40) | NR1H4MEN1KMT2APOLBAPEX1 | |
| SCHEMBL9735458 | 0.82 | NR1H4 (0.39) | NR1H4MEN1KMT2APOLBAPEX1 | |
| SCHEMBL9202844 | 0.82 | PDE4A (0.44) | HTTMALT1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9198312 | 0.82 | SMN1; SMN2 (0.34) | MEN1KMT2AHTTRAB9ASMN1; SMN2 | |
| SCHEMBL9204395 | 0.81 | LRRK2 (0.35) | HTTKDM4ETACR1 | |
| SCHEMBL8120777 | 0.79 | CASP6 (0.37) | NR1H4MEN1KMT2APOLBAPEX1 | |
| SCHEMBL9271111 | 0.77 | SMN1; SMN2 (0.48) | MEN1KMT2AHTTGAASMN1; SMN2 | |
| SCHEMBL8123714 | 0.76 | CASP6 (0.37) | NR1H4MEN1KMT2APOLBAPEX1 | |
| SCHEMBL9147582 | 0.75 | KMT2A (0.40) | NR1H4MEN1KMT2APOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514935-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-11-08 | — | — | EP | claimed |
| EP-0514935-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | claimed |
| JP-5178850-A | — | — | None | — | — | JP | disclosed |
| EP-0514935-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-11-08 | — | — | EP | disclosed |
| US-5236935-A | Hypotensive agents | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-08-17 | — | — | US | disclosed |
| JP-H05178850-A | BENZOPYRAN DERIVATIVE, ITS PREPARATION AND ANTIHYPERTENSIVE AGENT | KOREA RES INST CHEM TECHNOL | 1993-07-20 | — | — | JP | disclosed |
| EP-0514935-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |