Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007551 | 1.00 | MAPK1 (0.63) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL8007579 | 0.81 | MAPK1 (0.70) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL8538968 | 0.81 | MAPK1 (0.70) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL8538845 | 0.81 | MAPK1 (0.70) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL8146997 | 0.79 | MAPK1 (0.58) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL7916942 | 0.78 | MAPK1 (1.00) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL7994941 | 0.78 | MAPK1 (1.00) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL2534650 | 0.78 | MAPK1 (1.00) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL2504692 | 0.78 | MAPK1 (1.00) | MAPK1CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL4383952 | 0.78 | MAPK1 (1.00) | MAPK1CYP3A4MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168097-B2 | Photochemical methods of making cyclobutane boronates and related compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200223870-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-07-16 | — | — | US | disclosed |
| US-10618917-B2 | Photochemical methods of making cyclobutane boronates and related compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190040085-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-02-07 | — | — | US | disclosed |
| EP-0387196-B1 | Complexes with optically active ligands, process for their preparation and their use | CIBA GEIGY AG (CH) | 1995-05-03 | — | — | EP | disclosed |
| US-5047557-A | Complexes having optically active ligands, a process for their preparation and their use | CIBA-GEIGY CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168097-B2 | Photochemical methods of making cyclobutane boronates and related compounds | BLVRB, CYP11B2, CYP11B1 | MAPK1 1889/4885CYP3A4 78/4885MEN1 643/4885 |
| US-20190040085-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | BLVRB, CYP11B1, CYP11B2 | MAPK1 1887/4885CYP3A4 78/4885MEN1 619/4885 |
| US-10618917-B2 | Photochemical methods of making cyclobutane boronates and related compounds | BLVRB, CYP11B2, CYP11B1 | MAPK1 1889/4885CYP3A4 78/4885MEN1 643/4885 |
| US-20200223870-A1 | PHOTOCHEMICAL METHODS OF MAKING CYCLOBUTANE BORONATES AND RELATED COMPOUNDS | BLVRB, CYP11B2, CYP11B1 | MAPK1 1889/4885CYP3A4 78/4885MEN1 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.