Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 6/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802196 | 0.81 | HIF1A (0.43) | CA12CA9PTGS1PTGS2MAPT | |
| SCHEMBL6986044 | 0.79 | CA2 (0.40) | CA12CA9PTGS1PTGS2MEN1 | |
| SCHEMBL6982323 | 0.79 | CA2 (0.40) | CA12CA9PTGS1PTGS2MEN1 | |
| SCHEMBL21257372 | 0.78 | PTGS1 (0.37) | CA12CA9PTGS1PTGS2MEN1 | |
| SCHEMBL6981088 | 0.77 | NPSR1 (0.43) | CA12CA9PTGS1PTGS2XDH | |
| SCHEMBL9206139 | 0.74 | CA12 (0.40) | CA12CA9PTGS1PTGS2XDH | |
| SCHEMBL6980030 | 0.73 | HTR2C (0.41) | PTGS1PTGS2MEN1MAPTTSHR | |
| SCHEMBL12748472 | 0.73 | HTR2C (0.41) | PTGS1PTGS2MEN1MAPTTSHR | |
| SCHEMBL6980368 | 0.73 | HTR2C (0.41) | PTGS1PTGS2MEN1MAPTTSHR | |
| SCHEMBL9205782 | 0.73 | CA9 (0.44) | CA12CA9PTGS1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514935-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-11-08 | — | — | EP | disclosed |
| US-5236935-A | Hypotensive agents | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-08-17 | — | — | US | disclosed |
| EP-0514935-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |