Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198008 | 0.83 | CHRM4 (0.39) | NPC1HSD11B1CHRM4ALDH1A1HPGD | |
| SCHEMBL9202337 | 0.78 | DPP4 (0.36) | NPC1ALOX5ALDH1A1HPGDRAB9A | |
| SCHEMBL9251236 | 0.78 | ALDH1A1 (0.49) | NPC1CHRM4ALDH1A1HPGDRAB9A | |
| SCHEMBL9254522 | 0.75 | NPC1 (0.51) | NPC1ALDH1A1HPGDRAB9AGAA | |
| SCHEMBL9202295 | 0.73 | ALOX5 (0.44) | NPC1HSD11B1ALOX5ALDH1A1HPGD | |
| SCHEMBL12669759 | 0.73 | RAB9A (0.53) | NPC1HSD11B1CHRM4ALDH1A1HPGD | |
| SCHEMBL9198002 | 0.69 | ALDH1A1 (0.44) | NPC1CHRM4ALDH1A1HPGDRAB9A | |
| SCHEMBL9199237 | 0.68 | NPC1 (0.49) | NPC1ALDH1A1HPGDRAB9AGAA | |
| SCHEMBL3252705 | 0.68 | ALOX5 (0.39) | NPC1HSD11B1ALOX5ALDH1A1HPGD | |
| SCHEMBL12057434 | 0.67 | CHRM4 (0.39) | NPC1CHRM4ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463444-B1 | Dicarboxylic acid imides as herbicides | BASF AG (DE) | 1995-08-30 | — | — | EP | disclosed |
| EP-0463444-A1 | Dicarboxylic acid imides as herbicides | BASF Aktiengesellschaft (DE) | 1992-01-02 | — | — | EP | disclosed |