SCHEMBL920172

SCHEMBL920172

O=C(NCc1ccc(Oc2ccccc2)cc1)c1ccc(Cl)nc1Cl

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.57
HPGD P15428 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
ALDH1A1 P00352 1/20 0.57
GAA P10253 1/20 0.57
ATM Q13315 1/20 0.57
MAPK14 Q16539 4/20 0.53
CYP3A4 P08684 2/20 0.53
LMNA P02545 1/20 0.53
MMP13 P45452 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MAPK8 P45983 1/20 0.51
KLKB1 P03952 2/20 0.51
KLK1 P06870 2/20 0.51
ADORA2A P29274 1/20 0.49
APEX1 P27695 1/20 0.47
EPHX2 P34913 1/20 0.46
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921509 0.90 HPGD (0.55) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL2907928 0.88 ADORA2A (0.60) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL920767 0.88 MAPK14 (0.57) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL920309 0.88 HPGD (0.55) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL921250 0.82 HTT (0.54) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL922515 0.80 HPGD (0.53) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL920887 0.79 HTT (0.51) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL920934 0.78 MAPK14 (0.49) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL921968 0.78 MAPK14 (0.52) HTTHPGDL3MBTL1ALDH1A1GAA
SCHEMBL920412 0.78 MAPK14 (0.54) HTTHPGDL3MBTL1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HTT 2561/4885HPGD 1273/4885L3MBTL1 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.