SCHEMBL920309

SCHEMBL920309

Nc1nc(Cl)ccc1C(=O)NCc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
HTT P42858 2/20 0.55
ALDH1A1 P00352 1/20 0.55
GAA P10253 1/20 0.55
ATM Q13315 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MAPK14 Q16539 3/20 0.51
LMNA P02545 1/20 0.51
CYP3A4 P08684 1/20 0.51
MMP13 P45452 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GALR3 O60755 1/20 0.49
NR2F2 P24468 1/20 0.49
MAPK8 P45983 1/20 0.49
KLKB1 P03952 2/20 0.48
KLK1 P06870 1/20 0.48
ADORA2A P29274 1/20 0.47
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922515 0.90 HPGD (0.53) HPGDHTTALDH1A1GAAATM
SCHEMBL920172 0.88 HTT (0.57) HPGDHTTALDH1A1GAAATM
SCHEMBL1680425 0.87 KLKB1 (0.52) HTTALDH1A1L3MBTL1LMNASMN1; SMN2
SCHEMBL13070867 0.86 ADORA2A (0.53) HPGDALDH1A1GAAL3MBTL1LMNA
SCHEMBL921469 0.86 MAPK14 (0.52) HPGDHTTALDH1A1GAAATM
SCHEMBL921509 0.86 HPGD (0.55) HPGDHTTALDH1A1GAAATM
SCHEMBL919964 0.86 MAPK14 (0.57) HPGDHTTALDH1A1GAAATM
SCHEMBL12907971 0.85 MAPK14 (0.50) HPGDHTTALDH1A1GAAATM
SCHEMBL12907961 0.85 MAPK14 (0.50) HPGDHTTALDH1A1GAAATM
SCHEMBL1681250 0.84 GALR3 (0.50) HPGDALDH1A1L3MBTL1LMNAGALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885HTT 2561/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.