Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204354 | 0.82 | CYP1A2 (0.44) | CYP1A2CYP2C19KMT2ATSHRNR4A2 | |
| SCHEMBL28965242 | 0.81 | CYP1A2 (0.50) | CYP1A2CYP2C19KMT2ATSHRNR4A2 | |
| SCHEMBL10184712 | 0.81 | KMT2A (0.53) | CYP1A2CYP2C19KMT2ATSHRLMNA | |
| SCHEMBL4701434 | 0.80 | RAB9A (0.49) | KMT2ATSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL27941481 | 0.79 | SMN1; SMN2 (0.38) | LMNAKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL9196622 | 0.79 | CYP1A2 (0.43) | CYP1A2CYP2C19KMT2ATSHRLMNA | |
| SCHEMBL26654708 | 0.79 | CYP1A2 (0.49) | CYP1A2CYP2C19KMT2ATSHRLMNA | |
| SCHEMBL17895911 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP2C19KMT2ATSHRLMNA | |
| SCHEMBL3436120 | 0.79 | CYP1A2 (0.51) | CYP1A2CYP2C19KMT2ATSHRLMNA | |
| SCHEMBL9105724 | 0.78 | CYP1A2 (0.48) | CYP1A2CYP2C19KMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | disclosed |
| EP-0087780-B2 | Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL IND LTD (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-4954164-A | Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |