Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573566 | 0.84 | RAB9A (0.50) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL1458129 | 0.83 | ALDH1A1 (0.50) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL1406834 | 0.83 | NPC1 (0.49) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL561034 | 0.81 | RAB9A (0.62) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL4016524 | 0.81 | RAB9A (0.48) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL26102129 | 0.81 | LMNA (0.51) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL16229739 | 0.81 | RAB9A (0.48) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL8986609 | 0.81 | RAB9A (0.48) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL2315523 | 0.81 | RAB9A (0.48) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL10490542 | 0.81 | RAB9A (0.48) | RAB9ANPC1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112441978-B | Preparation method of 1-methyl-5-hydroxypyrazole-4-carboxylic acid ethyl ester | 江西天宇化工有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-112441978-A | Preparation method of 1-methyl-5-hydroxypyrazole-4-carboxylic acid ethyl ester | 江西天宇化工有限公司 | 2021-03-05 | — | — | CN | claimed |
| JP-6040824-A | — | — | None | — | — | JP | disclosed |
| JP-6009316-A | — | — | None | — | — | JP | disclosed |
| JP-58174369-A | — | — | None | — | — | JP | disclosed |
| US-20260132127-A1 | NOVEL SPIRO COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2026-05-14 | — | — | US | disclosed |
| WO-2025090758-A1 | AHR AGONISTS | ELI LILLY AND COMPANY (US) | 2025-05-01 | — | — | WO | disclosed |
| WO-2024153155-A1 | DOUBLE-HETEROCYCLIC WRN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都微芯药业有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-118176179-A | Novel spiro compounds | 田边三菱制药株式会社 | 2024-06-11 | — | — | CN | disclosed |
| CN-116669551-A | Agrochemical compositions with improved drift, absorption and rain resistance | 拜耳公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-0087780-B2 | Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL IND LTD (JP) | 1995-02-15 | — | — | EP | disclosed |
| JP-H0640824-A | PYRAZOLESULFONYLUREA DERIVATIVE, ITS PRODUCTION AND SELECTIVE HERBICIDE COMPRISING THE SAME DERIVATIVE | NISSAN CHEM IND LTD | 1994-02-15 | — | — | JP | disclosed |
| JP-H069316-A | PYRAZOLESULFONYLUREA DERIVATIVE, ITS PRODUCTION AND SELECTIVE HERBICIDE CONTAINING THE SAME DERIVATIVE | NISSAN CHEM IND LTD | 1994-01-18 | — | — | JP | disclosed |
| US-4954164-A | Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4792565-A | Pyrazolecarbonylamine derivatives and agricultural and horticultural fungicides containing said compounds | MITSUI TOATSU CHEMICALS, INC. (JP) | 1988-12-20 | — | — | US | disclosed |
| US-4643757-A | PREFERENTIAL | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1987-02-17 | — | — | US | disclosed |
| US-4557753-A | Herbicidal 4-benzoyl-1-methyl-5-phenylalkoxy pyrazoles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-12-10 | — | — | US | disclosed |
| JP-S58174369-A | 1-METHYL-5-HYDROXYPYRAZOLE-4-CARBOXYLIC LOWER ALKYL ESTER AND ITS PREPARATION | NISSAN CHEM IND LTD | 1983-10-13 | — | — | JP | disclosed |
| JP-H00640824-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132127-A1 | NOVEL SPIRO COMPOUND | TRHR, NR3C2, THRB | RAB9A 451/4885NPC1 457/4885KDM4E 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.