Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 5/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31312595 | 0.73 | KIF11 (0.46) | MAPTKMT2APTGS1PTGS2MAP4K4 | |
| SCHEMBL15263671 | 0.73 | KIF11 (0.46) | MAPTKMT2APTGS1PTGS2MAP4K4 | |
| SCHEMBL9202204 | 0.71 | ALOX5 (0.52) | MAPTMEN1KMT2ASMN1; SMN2KMO | |
| SCHEMBL16385239 | 0.71 | TLR8 (0.57) | MAPTMEN1KMT2AKMOHSD17B1 | |
| SCHEMBL5700322 | 0.71 | PIK3CG (0.50) | MAPTMEN1KMT2ASMN1; SMN2PTGS1 | |
| SCHEMBL2382865 | 0.70 | PIM1 (0.36) | MAPTPTGS1PTGS2MAP4K4HSD17B1 | |
| SCHEMBL827247 | 0.69 | CCR1 (0.48) | MAPTSMN1; SMN2KMOPTGS1PTGS2 | |
| SCHEMBL15947898 | 0.69 | PIM1 (0.57) | MAPTSMN1; SMN2KMOMAP4K4PIM1 | |
| SCHEMBL24700310 | 0.68 | TGFBR1 (0.42) | MAPTMEN1KMT2AMAP4K4PIM1 | |
| SCHEMBL29994506 | 0.68 | TGFBR1 (0.42) | MAPTMEN1KMT2AMAP4K4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304155-B1 | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions | ZENECA PHARMA SA (FR) | 1995-11-15 | — | — | EP | disclosed |
| US-5013730-A | Antibiotics | ICI-PHARMA (FR) | 1991-05-07 | — | — | US | disclosed |