Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424444 | 0.75 | ALDH1A1 (0.37) | TBXAS1ALDH1A1EGLN3FAAHMGLL | |
| SCHEMBL13448304 | 0.70 | HTT (0.36) | TBXAS1ALDH1A1EGLN3FAAHMGLL | |
| SCHEMBL28770447 | 0.69 | PDE4A (0.43) | TBXAS1ALDH1A1EGLN3FAAHMGLL | |
| SCHEMBL2143878 | 0.69 | TBXAS1 (0.37) | TBXAS1ALDH1A1EGLN3FAAHMGLL | |
| SCHEMBL7780136 | 0.69 | ALDH1A1 (0.36) | TBXAS1ALDH1A1EGLN3FAAHMGLL | |
| SCHEMBL2003497 | 0.69 | — | — | |
| SCHEMBL1905122 | 0.68 | ALDH1A1 (0.37) | TBXAS1ALDH1A1EGLN3FAAHMGLL | |
| SCHEMBL16974556 | 0.68 | ALDH1A1 (0.33) | TBXAS1ALDH1A1EGLN3FAAHMGLL | |
| SCHEMBL13587345 | 0.67 | TBXAS1 (0.40) | TBXAS1ALDH1A1EGLN3FAAHMGLL | |
| SCHEMBL18775172 | 0.67 | TBXAS1 (0.40) | TBXAS1ALDH1A1EGLN3FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643685-A1 | PALLADIUM CATALYZED ADDITION OF AMINES TO 3,4-EPOXY-1-BUTENE. | EASTMAN CHEM CO (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5326873-A | Catalyst selectivity | EASTMAN KODAK COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1993025516-A1 | PALLADIUM CATALYZED ADDITION OF AMINES TO 3,4-EPOXY-1-BUTENE | EASTMAN CHEMICAL COMPANY (US) | 1993-12-23 | — | — | WO | disclosed |