Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9203031 | 0.98 | KDM4E (0.45) | KDM4EMAPTPOLBTNFSF11ALDH1A1 | |
| SCHEMBL9826659 | 0.87 | PNMT (0.44) | KDM4EMAPTPOLB | |
| Bromide SCHEMBL9827389 | 0.86 | PNMT (0.43) | KDM4EMAPTPOLB | |
| SCHEMBL9202430 | 0.81 | MAPT (0.39) | KDM4EMAPTPOLBTNFSF11ALDH1A1 | |
| SCHEMBL10798207 | 0.77 | ACHE (0.47) | KDM4EMAPTPOLBALDH1A1GAA | |
| SCHEMBL10797761 | 0.77 | GRIN2D (0.42) | KDM4EMAPTPOLBTNFSF11ALDH1A1 | |
| SCHEMBL16715040 | 0.77 | PGR (0.49) | KDM4EMAPTPOLBTNFSF11ALDH1A1 | |
| SCHEMBL6275593 | 0.77 | TNFSF11 (0.67) | KDM4EMAPTTNFSF11ALDH1A1TSHR | |
| Bromide SCHEMBL9204144 | 0.76 | ACHE (0.46) | KDM4EMAPTPOLBALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL27919833 | 0.76 | ACHE (0.46) | KDM4EMAPTPOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186187-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-02-26 | — | — | EP | claimed |
| EP-0186187-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-02 | — | — | EP | claimed |
| EP-0452987-B1 | Isoindoline derivatives | BANYU PHARMA CO LTD (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0186187-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-02-26 | — | — | EP | disclosed |
| EP-0452987-A1 | Isoindoline derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4987235-A | Isoindoline derivatives and processes for their preparation | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958029-A | Process for the production of isoindoline derivatives, novel intermediates and process for their production | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0275064-A2 | Process for the production of isoindoline derivatives, novel intermediates and process for their production | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-07-20 | — | — | EP | disclosed |
| EP-0227986-A1 | Isoindoline derivatives and processes for their preparation | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |
| US-4677100-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0186187-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-02 | — | — | EP | disclosed |