Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803750 | 0.89 | KDM4E (0.40) | LMNAKDM4ECYP2C19TSHRNPSR1 | |
| SCHEMBL1802401 | 0.78 | HSD17B10 (0.42) | LMNAKDM4ECYP2C19TSHRNPSR1 | |
| SCHEMBL10902746 | 0.75 | MMP9 (0.33) | LMNAKDM4ECYP2C19SMN1; SMN2 | |
| SCHEMBL21985093 | 0.73 | KDM4E (0.35) | LMNAKDM4ECYP2C19TSHRNPSR1 | |
| SCHEMBL8823121 | 0.72 | LMNA (0.41) | LMNAKDM4ECYP2C19TSHRNPSR1 | |
| SCHEMBL11165943 | 0.72 | — | — | |
| SCHEMBL1803803 | 0.70 | KDM4E (0.40) | LMNAKDM4ECYP2C19TSHRNPSR1 | |
| SCHEMBL1802571 | 0.69 | HSD17B10 (0.42) | LMNAKDM4ECYP2C19SMN1; SMN2 | |
| SCHEMBL265547 | 0.69 | KDM4E (0.35) | LMNAKDM4ECYP2C19TSHRNPSR1 | |
| SCHEMBL6278690 | 0.68 | KDM4E (0.38) | LMNAKDM4ECYP2C19TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434079-B1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ATOCHEM NORTH AMERICA (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5043372-A | Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0434079-A1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0202001-B1 | PROCESS FOR THE PRODUCTION OF 2,2,6,6,-TETRAALKYL 4 PIPERIDYLAMINES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1990-11-22 | — | — | EP | disclosed |
| EP-0208455-A1 | Process for the production of 2,2,6,6-tetraalkyl-4-piperidylamines | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1987-01-14 | — | — | EP | disclosed |
| EP-0202001-A2 | Process for the production of 2,2,6,6,-tetraalkyl 4 piperidylamines | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1986-11-20 | — | — | EP | disclosed |
| US-4607104-A | AMINATION OF PIPERIDONE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| US-4605743-A | REACTING AN AMINE WITH A 2,2,6,6-TETRAALKYL-4-PIPERIDONE USING A PALLADIUM HYDROGENATION CATALYST | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4046736-A | 1,3-BIS[(2,2,6,6-Tetraalkyl-4-piperidylidene)amino]guanidines as light stabilizers for polyolefins | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |