Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637026 | 0.76 | AHR (0.36) | — | |
| SCHEMBL4523362 | 0.74 | CSNK2A2 (0.36) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL29410754 | 0.74 | CSNK2A2 (0.36) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL29577058 | 0.73 | KDR (0.39) | HSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL23412218 | 0.72 | NT5E (0.33) | — | |
| SCHEMBL2795974 | 0.69 | CYP2A6 (0.44) | TSHR | |
| SCHEMBL2797388 | 0.68 | L3MBTL1 (0.38) | HSD17B10ALDH1A1 | |
| SCHEMBL4467529 | 0.68 | ACHE (0.41) | TSHRHSD17B10ALDH1A1 | |
| SCHEMBL30489827 | 0.68 | L3MBTL1 (0.38) | HSD17B10ALDH1A1 | |
| SCHEMBL9796610 | 0.68 | ESR2 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304155-B1 | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions | ZENECA PHARMA SA (FR) | 1995-11-15 | — | — | EP | disclosed |
| US-5013730-A | Antibiotics | ICI-PHARMA (FR) | 1991-05-07 | — | — | US | disclosed |
| EP-0304155-A2 | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions | ZENECA Pharma S.A. (FR) | 1989-02-22 | — | — | EP | disclosed |