SCHEMBL920240

SCHEMBL920240

CCc1csc(Oc2ccc(CNC(=O)c3cccnc3N)cc2)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 4/20 0.48
▸ LMNA P02545 3/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ ALDH1A1 P00352 2/20 0.47
▸ MAPK8 P45983 3/20 0.46
▸ EGLN1 Q9GZT9 1/20 0.42
▸ POLB P06746 2/20 0.42
▸ GAA P10253 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919888 0.89 ALDH1A1 (0.48) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL922454 0.85 HPGD (0.53) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL920673 0.85 HPGD (0.48) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL920473 0.83 HPGD (0.57) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL921013 0.83 HPGD (0.50) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL920794 0.82 MAPK8 (0.50) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL922834 0.82 HPGD (0.48) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL922025 0.81 ALDH1A1 (0.58) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL920905 0.81 MAPK8 (0.53) HPGDLMNASMN1; SMN2ALDH1A1MAPK8
SCHEMBL920730 0.80 MAPK8 (0.50) HPGDLMNASMN1; SMN2ALDH1A1MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 — — US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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