Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31272103 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL22792110 | 0.78 | GPR3 (0.60) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL13704044 | 0.78 | GPR3 (0.60) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL13704120 | 0.78 | GPR3 (0.60) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL14579466 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL2173695 | 0.76 | MEN1 (0.56) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL22623757 | 0.76 | MEN1 (0.56) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL13206625 | 0.76 | MEN1 (0.56) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL29691072 | 0.76 | DRD4 (0.48) | KDM4EALDH1A1GAAHTTLMNA | |
| SCHEMBL9203076 | 0.75 | HTT (0.51) | KDM4EALDH1A1GAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | disclosed |