SCHEMBL92033

SCHEMBL92033

O=C(O)c1ccc2sc(S(=O)(=O)C(Br)(Br)Br)nc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
CA2 P00918 3/20 0.44
HDAC6 Q9UBN7 4/20 0.41
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
KDM4E B2RXH2 4/20 0.40
NFKB1 P19838 2/20 0.40
NFKB2 Q00653 2/20 0.40
RELA Q04206 2/20 0.40
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 3/20 0.40
TRPV1 Q8NER1 1/20 0.39
POLB P06746 2/20 0.39
ALDH1A1 P00352 2/20 0.38
GAA P10253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23540263 0.82 NPC1 (0.65) NPC1RAB9ASMN1; SMN2CA2HDAC6
Hydrochloric Acid SCHEMBL11583456 0.81 NPC1 (0.63) NPC1RAB9ASMN1; SMN2CA2HDAC6
SCHEMBL25862169 0.81 CA2 (0.68) NPC1RAB9ACA2KDM4EPOLB
SCHEMBL11973204 0.78 DYRK1A (0.46) NPC1RAB9ASMN1; SMN2CA2KDM4E
SCHEMBL25252536 0.77 NPC1 (0.70) NPC1RAB9ASMN1; SMN2HDAC6HDAC3
SCHEMBL30063475 0.77 NPC1 (0.70) NPC1RAB9ASMN1; SMN2HDAC6HDAC3
SCHEMBL13908170 0.75 DYRK1A (0.49) CA2TRPV1POLBDYRK1A
Hydrochloric Acid SCHEMBL11596610 0.75 RAB9A (0.68) NPC1RAB9ASMN1; SMN2CA2HDAC6
SCHEMBL3275548 0.73 PSMB8 (0.66) NPC1RAB9ASMN1; SMN2CA2LMNA
SCHEMBL1105986 0.73 NPC1 (1.00) NPC1RAB9ASMN1; SMN2KDM4ENFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142087-A1 LAMINATE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-8127675-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20100005989-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION 2010-01-14 US disclosed
EP-1557262-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2007-11-14 EP disclosed
US-20070092836-A1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-04-26 US disclosed
US-20070092836-A1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-04-26 US disclosed