Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232798 | 0.89 | PTGS2 (0.58) | PTGS2ALOX5PTGS1CYP2C9AOC3 | |
| SCHEMBL9203208 | 0.88 | PTGS2 (0.53) | PTGS2ALOX5PTGS1CYP2C9AOC3 | |
| SCHEMBL9208788 | 0.88 | PTGS2 (0.57) | PTGS2ALOX5PTGS1CYP2C9AOC3 | |
| Hydrochloric Acid SCHEMBL9740507 | 0.88 | PTGS2 (0.57) | PTGS2ALOX5PTGS1CYP2C9AOC3 | |
| SCHEMBL7240058 | 0.86 | PTGS2 (0.55) | PTGS2ALOX5PTGS1CYP2C9AOC3 | |
| SCHEMBL9201497 | 0.85 | ALOX5 (0.51) | PTGS2ALOX5PTGS1CYP2C9AOC3 | |
| SCHEMBL7459996 | 0.85 | PTGS2 (0.62) | PTGS2ALOX5PTGS1CYP2C9 | |
| SCHEMBL9203630 | 0.85 | PTGS2 (0.65) | PTGS2ALOX5PTGS1CYP2C9 | |
| SCHEMBL9209927 | 0.85 | AOC3 (0.60) | PTGS2ALOX5PTGS1CYP2C9AOC3 | |
| SCHEMBL9210134 | 0.84 | PTGS2 (0.48) | PTGS2ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418845-B1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5134142-A | PYRAZOLE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |