Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364715 | 0.78 | TDP1 (0.48) | MAPK1CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL24828159 | 0.72 | PTGS1 (0.50) | FBP1PTGS2ALOX5PTGS1CA2 | |
| SCHEMBL9724130 | 0.72 | PDE7A (0.54) | FBP1PDE7AALDH1A1TSHRTDP1 | |
| SCHEMBL9018798 | 0.71 | HAO1 (0.44) | FBP1MAPK1CA2ALDH1A1HSD17B10 | |
| SCHEMBL7926405 | 0.71 | ALDH1A1 (0.41) | MAPK1CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL2432241 | 0.71 | FBP1 (0.68) | FBP1PTGS2PDE7AALDH1A1TSHR | |
| SCHEMBL943247 | 0.69 | TDP1 (0.48) | CA2ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL9086463 | 0.69 | FBP1 (0.43) | FBP1MAPK1ALDH1A1TSHRNPC1 | |
| SCHEMBL27274014 | 0.69 | FBP1 (0.39) | FBP1PDE7AMAPK1CA2ALDH1A1 | |
| SCHEMBL28530136 | 0.68 | FBP1 (0.42) | FBP1PTGS2PDE7AGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462812-B1 | Pyran derivatives as inhibitors of 5-lipoxygenase | ZENECA LTD (GB) | 1995-12-06 | — | — | EP | disclosed |
| EP-0462812-A2 | Pyran derivatives as inhibitors of 5-lipoxygenase | ZENECA LIMITED (GB) | 1991-12-27 | — | — | EP | disclosed |