Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.54 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 2/20 | 0.42 |
| ▸ | LDHB | P07195 | 2/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199082 | 0.79 | PDE7A (0.61) | PDE7AFBP1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL8308899 | 0.77 | PDE7A (0.58) | PDE7AFBP1KDM4ENPSR1ALDH1A1 | |
| SCHEMBL29543966 | 0.75 | RHEB (0.55) | FBP1LMNAKDM4ENPSR1L3MBTL1 | |
| SCHEMBL6915666 | 0.75 | RHEB (0.55) | FBP1LMNAKDM4ENPSR1L3MBTL1 | |
| SCHEMBL2432241 | 0.75 | FBP1 (0.68) | PDE7AFBP1LMNAKDM4EL3MBTL1 | |
| SCHEMBL30548744 | 0.73 | RHEB (0.53) | FBP1LMNAKDM4ENPSR1L3MBTL1 | |
| SCHEMBL9018798 | 0.72 | HAO1 (0.44) | FBP1ALDH1A1MAPTHAO1DHFR | |
| SCHEMBL9203553 | 0.72 | FBP1 (0.42) | PDE7AFBP1LMNANPSR1ALDH1A1 | |
| SCHEMBL28530136 | 0.72 | FBP1 (0.42) | PDE7AFBP1 | |
| SCHEMBL1466222 | 0.72 | FBP1 (0.42) | PDE7AFBP1LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |