Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CCR9 | P51686 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884470 | 0.83 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL8884464 | 0.83 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL9210620 | 0.82 | TBXA2R (0.56) | TBXAS1TBXA2RHDAC8EGFRPTGS2 | |
| SCHEMBL8883349 | 0.77 | HDAC8 (0.52) | TBXAS1TBXA2RHDAC8HDAC6 | |
| SCHEMBL8883245 | 0.76 | TBXAS1 (0.80) | TBXAS1TBXA2R | |
| SCHEMBL8883244 | 0.76 | TBXAS1 (0.80) | TBXAS1TBXA2R | |
| SCHEMBL462300 | 0.76 | HDAC8 (0.81) | TBXAS1TBXA2RHDAC8HDAC6 | |
| SCHEMBL442975 | 0.76 | HDAC8 (1.00) | TBXA2RHDAC8HDAC6 | |
| SCHEMBL8883009 | 0.75 | TBXAS1 (0.88) | TBXAS1TBXA2R | |
| SCHEMBL8884819 | 0.75 | TBXAS1 (0.88) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397044-B1 | Arylsulfonamides, medicines containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1995-12-27 | — | — | EP | disclosed |
| EP-0397044-A2 | Arylsulfonamides, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-11-14 | — | — | EP | disclosed |