Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932417 | 0.79 | CHRNB2 (0.35) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL27838683 | 0.78 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL8932390 | 0.77 | ALDH1A1 (0.33) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL9384993 | 0.75 | ALDH1A1 (0.40) | ACEDDB1CRBNALDH1A1NFKB1 | |
| SCHEMBL10954717 | 0.75 | ALDH1A1 (0.40) | ACEDDB1CRBNALDH1A1NFKB1 | |
| SCHEMBL10954720 | 0.75 | ALDH1A1 (0.40) | ACEDDB1CRBNALDH1A1NFKB1 | |
| SCHEMBL8932630 | 0.73 | CHRNB2 (0.32) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3741280 | 0.73 | CRBN (0.44) | MTNR1ADDB1CRBNALDH1A1 | |
| SCHEMBL6397894 | 0.72 | KMT2A (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL8759876 | 0.72 | KMT2A (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210883-B1 | Derivatives of penem | DAIICHI SEIYAKU CO (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-5079357-A | Bactericides | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| US-4962202-A | PENICILLIN INTERMEDIATES | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0210883-A2 | Derivatives of penem | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |