Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.70 |
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphenylmethanamine SCHEMBL115149 | 0.84 | KCNN4 (1.00) | KCNN4KIF11TSHRALDH1A1KMT2A | |
| SCHEMBL6000332 | 0.81 | KIF11 (0.47) | KCNN4KIF11NOTUMTSHRALDH1A1 | |
| Triphenylmethanamine SCHEMBL1508115 | 0.81 | KCNN4 (0.93) | KCNN4KIF11TSHRALDH1A1KMT2A | |
| Triphenylmethanamine SCHEMBL1508398 | 0.81 | KCNN4 (0.93) | KCNN4KIF11TSHRALDH1A1KMT2A | |
| Triphenylmethanamine SCHEMBL3317188 | 0.81 | KCNN4 (0.93) | KCNN4KIF11TSHRALDH1A1KMT2A | |
| Triphenylmethanamine SCHEMBL7661114 | 0.81 | KCNN4 (0.93) | KCNN4KIF11TSHRALDH1A1KMT2A | |
| Triphenylmethanamine SCHEMBL1508351 | 0.81 | KCNN4 (0.93) | KCNN4KIF11TSHRALDH1A1KMT2A | |
| Triphenylmethanamine SCHEMBL31146599 | 0.81 | KCNN4 (0.93) | KCNN4KIF11TSHRALDH1A1KMT2A | |
| Triphenylmethanamine SCHEMBL11023487 | 0.81 | KCNN4 (0.93) | KCNN4KIF11TSHRALDH1A1KMT2A | |
| SCHEMBL4339462 | 0.79 | NOTUM (0.50) | KCNN4KIF11NOTUMTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958018-A | REACTING A 3-HALOMETHYL-3-CEPHEM WITH A LEAD REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-09-18 | — | — | US | claimed |
| EP-0341694-B1 | Method for production of 3-exomethylenecepham derivatives | OTSUKA KAGAKU KK (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-4958018-A | REACTING A 3-HALOMETHYL-3-CEPHEM WITH A LEAD REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0341694-A2 | Method for production of 3-exomethylenecepham derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1989-11-15 | — | — | EP | disclosed |