Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344106 | 0.86 | CA2 (0.47) | ERN1CA2CA1PTPN1PTGS2 | |
| SCHEMBL31006760 | 0.84 | CA2 (0.67) | CA2CA1PTPN1PTGS2PTGS1 | |
| SCHEMBL31199174 | 0.80 | ERN1 (0.71) | ERN1CA2CA1PTPN1PTPRC | |
| SCHEMBL14853277 | 0.80 | HSP90AA1 (0.46) | ERN1CA2CA1PTGS2PTPN5 | |
| SCHEMBL31046785 | 0.79 | ADORA3 (0.45) | ERN1PTPN1PGRARPTPRC | |
| SCHEMBL9272705 | 0.79 | CA2 (0.59) | CA2CA1PTPN1PGRAR | |
| SCHEMBL30875145 | 0.78 | CA2 (0.64) | CA2CA1PTPN1PTGS2PTGS1 | |
| SCHEMBL3743489 | 0.78 | PTPRC (0.58) | ERN1CA2CA1PTPN1HTR7 | |
| SCHEMBL18593548 | 0.78 | PTPN5 (0.48) | ERN1PTPN1HTR7PTPRCPDK2 | |
| SCHEMBL11427045 | 0.77 | CA2 (0.57) | CA2CA1PTPN1ARPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382213-B1 | Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5053548-A | Containing hydroxy substituents; nervous system disorders | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0382213-A2 | Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4232043-A | HALO-, METHOXY-, METHYL- OR 4-NITRO PHENYL-SUBSTITUTED 2,6-DI(T-BUTYL) PHENOL | RIKER LABORATORIES, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4219501-A | Anti-inflammatory method | RIKER LABORATORIES, INC. (US) | 1980-08-26 | — | — | US | disclosed |
| US-4172151-A | 2,6-DI-TERT-BUTYL-PHENOL DERIVATIVES | RIKER LABORATORIES, INC. (US) | 1979-10-23 | — | — | US | disclosed |