Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 8/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205957 | 0.88 | ADRA1D (0.59) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9205182 | 0.87 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BCA1CA2 | |
| SCHEMBL9206070 | 0.87 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BCA1CA2 | |
| SCHEMBL9203733 | 0.87 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BCA1CA2 | |
| SCHEMBL9210885 | 0.87 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BCA1CA2 | |
| SCHEMBL9205645 | 0.86 | DRD2 (0.53) | — | |
| SCHEMBL9210884 | 0.86 | DRD2 (0.53) | — | |
| SCHEMBL9204524 | 0.86 | ADRA1D (0.62) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9205633 | 0.86 | DRD2 (0.53) | — | |
| SCHEMBL9203919 | 0.86 | DRD2 (0.48) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | claimed |
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0520674-A1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |