Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210884 | 1.00 | DRD2 (0.53) | DRD2DRD4DRD3 | |
| SCHEMBL9205645 | 1.00 | DRD2 (0.53) | DRD2DRD4DRD3 | |
| SCHEMBL9203919 | 0.96 | DRD2 (0.48) | DRD2DRD4DRD3 | |
| SCHEMBL9214181 | 0.89 | CA1 (0.59) | — | |
| SCHEMBL9207882 | 0.89 | CA1 (0.59) | — | |
| SCHEMBL9205652 | 0.88 | CA2 (0.49) | DRD2DRD4DRD3 | |
| SCHEMBL9207245 | 0.88 | ADRA1D (0.49) | — | |
| SCHEMBL9207871 | 0.88 | ADRA1D (0.49) | — | |
| SCHEMBL9205887 | 0.88 | ADRA1D (0.49) | — | |
| SCHEMBL9207474 | 0.87 | ADRA1D (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | claimed |
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0520674-A1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5126366-A | Antidepressants, antipsychotics, anxiolytic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |