Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 7/20 | 0.82 |
| ▸ | PGK2 | P07205 | 7/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300677 | 0.80 | PGK1 (0.78) | PGK1PGK2LMNASMN1; SMN2MMP2 | |
| SCHEMBL11301473 | 0.80 | PGK1 (0.78) | PGK1PGK2MMP2HDAC4HDAC7 | |
| SCHEMBL4093802 | 0.79 | SRC (0.60) | PGK1PGK2CYP1A2LMNAMAPT | |
| SCHEMBL19638012 | 0.79 | ACP3 (0.58) | PGK1PGK2CYP1A2LMNAMAPT | |
| SCHEMBL4811089 | 0.79 | PGK1 (0.77) | PGK1PGK2TSHR | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL5746553 | 0.77 | PGK1 (0.59) | PGK1PGK2CYP1A2LMNAMAPT | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL292744 | 0.77 | PGK1 (0.59) | PGK1PGK2CYP1A2LMNAMAPT | |
| SCHEMBL11476691 | 0.77 | PGK1 (0.65) | PGK1PGK2MMP8MMP14CA14 | |
| SCHEMBL5623742 | 0.76 | PGK1 (0.78) | PGK1PGK2CYP1A2LMNAMAPT | |
| Water SCHEMBL9146143 | 0.76 | SRC (0.56) | PGK1PGK2CYP1A2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110734364-A | Synthesis method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone | 上海生农生化制品股份有限公司 | 2020-01-31 | — | — | CN | disclosed |
| EP-0538310-B1 | ETHYNYLBENZOTHIOPHENE PESTICIDES | FMC CORP (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0538310-A4 | ETHYNYLBENZOTHIOPHENE PESTICIDES | — | 1993-07-14 | — | — | EP | disclosed |
| EP-0538310-A1 | ETHYNYLBENZOTHIOPHENE PESTICIDES. | FMC CORP (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000672-A1 | ETHYNYLBENZOTHIOPHENE PESTICIDES | FMC CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |
| US-5073564-A | Photoactivated insecticides | FMC CORPORATION (US) | 1991-12-17 | — | — | US | disclosed |
| US-4826829-A | MITICIDES | FMC CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| WO-1988000467-A1 | 2-SUBSTITUTED ETHYNYL THIOPHENE PESTICIDES | FMC CORPORATION (US) | 1988-01-28 | — | — | WO | disclosed |
| US-4482731-A | Process for the preparation of trans-3-(z-2-chloro-2-aryl-vinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid derivatives, and the use of intermediate products in agents for compating pests | BAYER AKTIENGESELLSCHAFT (DE) | 1984-11-13 | — | — | US | disclosed |
| EP-0006205-B1 | PROCESS FOR THE PREPARATION OF CHLOROSTYRENECYCLOPROPANE CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0031915-A1 | Process for the production of haloalkenes | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| EP-0019719-A1 | Process for preparing alkenes, novel intermediates for their preparation and process for preparing them | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |
| EP-0006205-A1 | Process for the preparation of chlorostyrenecyclopropane carboxylic acid derivatives | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |