Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | PGK1 | P00558 | 2/20 | 0.50 |
| ▸ | PGK2 | P07205 | 2/20 | 0.50 |
| ▸ | MMP14 | P50281 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9146143 | 0.96 | SRC (0.56) | SRCCYP1A2LMNAMAPTTHRB | |
| SCHEMBL9301497 | 0.87 | SRC (0.75) | SRCCYP1A2LMNAMAPTTHRB | |
| SCHEMBL2730955 | 0.87 | CYP1A2 (0.47) | SRCCYP1A2LMNAMAPTTHRB | |
| Water SCHEMBL9146136 | 0.84 | MMP1 (0.46) | SRCCYP1A2LMNAMAPTTHRB | |
| SCHEMBL19638012 | 0.81 | ACP3 (0.58) | CYP1A2LMNAMAPTTHRBPMP22 | |
| SCHEMBL2171583 | 0.80 | SRC (0.65) | SRCMMP8PGK1PGK2MMP14 | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL5746553 | 0.79 | PGK1 (0.59) | CYP1A2LMNAMAPTTHRBPMP22 | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL292744 | 0.79 | PGK1 (0.59) | CYP1A2LMNAMAPTTHRBPMP22 | |
| SCHEMBL9204375 | 0.79 | PGK1 (0.82) | CYP1A2LMNAMAPTTHRBPMP22 | |
| SCHEMBL5936840 | 0.78 | SRC (0.62) | SRCCYP1A2LMNAMAPTPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293029-B2 | Colored conversion layers on metal surfaces | HENKEL AG & CO. KGAA (DE) | 2012-10-23 | — | — | US | disclosed |
| EP-2057303-B1 | CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION | HENKEL AG & CO KGAA (DE) | 2012-05-23 | — | — | EP | disclosed |
| US-20090214883-A1 | CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION | HENKEL AG & CO. KGAA (DE) | 2009-08-27 | — | — | US | disclosed |
| US-20060173099-A1 | Colored conversion layers on metal surfaces | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-08-03 | — | — | US | disclosed |
| US-4416877-A | Anti-atherosclerotic pharmaceutical compositions containing diphosphonate compounds | SYMPHAR S.A. (CH) | 1983-11-22 | — | — | US | disclosed |
| US-4371527-A | CIRCULATING HIGH DENSITY LIPOPROTEINS AND CLEARING CHOLESTEROL | SYMPHAR S.A. (CH) | 1983-02-01 | — | — | US | disclosed |
| EP-0015370-B1 | DIPHOSPHONATE OR PHOSPHATE-PHOSPHONATE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1983-01-12 | — | — | EP | disclosed |
| US-4309364-A | Diphosphonates | SYMPHAR S.A. (CH) | 1982-01-05 | — | — | US | disclosed |
| EP-0015370-A1 | Diphosphonate or phosphate-phosphonate derivatives and pharmaceutical compositions containing them | SYMPHAR S.A. (CH) | 1980-09-17 | — | — | EP | disclosed |