Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206405 | 0.83 | KDM4E (0.61) | KDM4EMAPTL3MBTL1TSHRALDH1A1 | |
| SCHEMBL8994512 | 0.76 | ALDH1A1 (0.52) | KDM4EMAPTL3MBTL1TSHRALDH1A1 | |
| SCHEMBL371069 | 0.74 | TSHR (0.54) | KDM4ETSHRCCND3CDK6CYP2D6 | |
| SCHEMBL28823820 | 0.74 | CNR2 (0.55) | MAPTL3MBTL1TSHRGBA1CCND3 | |
| SCHEMBL10141203 | 0.72 | — | — | |
| SCHEMBL21114388 | 0.72 | TSHR (0.57) | KDM4EMAPTTSHRCYP2D6NAPRT | |
| SCHEMBL10141202 | 0.72 | — | — | |
| SCHEMBL28298 | 0.72 | — | — | |
| SCHEMBL28462590 | 0.72 | KDM4C (0.50) | KDM4EMAPTL3MBTL1TSHRALDH1A1 | |
| SCHEMBL30880788 | 0.72 | KDM4C (0.50) | KDM4EMAPTL3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659186-A1 | INDOLIZINES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994005662-A1 | INDOLIZINES AS HERBICIDES | ZENECA LIMITED (GB) | 1994-03-17 | — | — | WO | disclosed |