Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541163 | 0.84 | ELANE (0.56) | ELANEHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL11815870 | 0.78 | ELANE (0.58) | ELANEHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL23142838 | 0.77 | ELANE (0.56) | ELANEHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL9541096 | 0.77 | ELANE (0.56) | ELANEHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL9339013 | 0.75 | ELANE (0.83) | ELANEHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL269329 | 0.74 | LMNA (0.80) | ELANEHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL26120207 | 0.74 | ELANE (0.62) | ELANEHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL524182 | 0.74 | CES1 (0.61) | HSD17B10MAPTPOLBALDH1A1TDP1 | |
| SCHEMBL9762610 | 0.73 | ELANE (0.67) | ELANEHSD17B10LMNAMEN1KMT2A | |
| SCHEMBL5831549 | 0.73 | ELANE (0.67) | ELANEHSD17B10LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489877-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | UPJOHN CO (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5302613-A | Antiatheroscleroic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones | THE UPJOHN COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| US-5252735-A | Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones | THE UPJOHN COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0489877-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES. | UPJOHN CO (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1992000290-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | THE UPJOHN COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |