Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212061 | 0.92 | USP2 (0.44) | USP2MEN1KMT2ATP53TSHR | |
| SCHEMBL9206323 | 0.91 | LMNA (0.43) | USP2MEN1KMT2ATP53TSHR | |
| SCHEMBL2404144 | 0.91 | ALDH1A1 (0.48) | USP2MEN1KMT2ATP53TSHR | |
| SCHEMBL9202552 | 0.88 | USP2 (0.40) | USP2MEN1KMT2ATP53TSHR | |
| SCHEMBL1052649 | 0.84 | ALDH1A1 (0.54) | USP2MEN1KMT2ATP53TSHR | |
| SCHEMBL3383370 | 0.80 | ALDH1A1 (0.50) | USP2MEN1KMT2ATP53TSHR | |
| SCHEMBL9204137 | 0.80 | USP2 (0.40) | USP2MEN1KMT2ATP53TSHR | |
| SCHEMBL9208292 | 0.77 | DNM1 (0.41) | USP2MEN1KMT2ATP53TSHR | |
| SCHEMBL4270142 | 0.75 | ALDH1A1 (0.54) | TSHRLMNACYP3A4ALDH1A1TDP1 | |
| SCHEMBL758110 | 0.75 | ALDH1A1 (0.54) | TSHRLMNACYP3A4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |