Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918956 | 0.94 | GAA (0.49) | GAALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7022574 | 0.92 | GAA (0.48) | GAALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11211411 | 0.92 | GAA (0.48) | GAALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28135662 | 0.92 | GAA (0.48) | GAALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL499133 | 0.88 | — | — | |
| SCHEMBL3688382 | 0.81 | MAPT (0.51) | GAALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL20634195 | 0.81 | MAPT (0.51) | GAALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL21392011 | 0.81 | MAPT (0.51) | GAALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL269528 | 0.81 | — | — | |
| 2-Thiophenenecarboxaldehyde SCHEMBL27772563 | 0.76 | MAPT (0.50) | GAALMNAALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093408-A | Benzylamine-containing 5, 6-heteroaromatic compounds useful against mycobacterial infections | 盐野义制药株式会社 | 2022-09-23 | — | — | CN | disclosed |
| CN-114401965-A | Benzylamine-containing 5, 6-heteroaromatic compounds useful against mycobacterial infections | 盐野义制药株式会社 | 2022-04-26 | — | — | CN | disclosed |
| CN-114206897-A | Convergent liquid phase synthesis of oligonucleotides | 比奥根MA公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-108834415-B | Substituted tricyclic 1, 4-benzodiazepine derivatives as allosteric modulators of group II metabotropic glutamate receptors | 多曼治疗学公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-113227070-A | ASK1 inhibitors | 比奥根MA公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-112105359-A | Pyrrolo [2,3-b ] pyrazine compounds as cccDNA inhibitors for the treatment of Hepatitis B Virus (HBV) infection | 豪夫迈·罗氏有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-107922423-B | Nitrogen-containing tricyclic derivatives having HIV replication inhibiting effect | 盐野义制药株式会社 | 2020-10-27 | — | — | CN | disclosed |
| CN-111138458-A | Nitrogen-containing tricyclic derivatives having HIV replication inhibiting effect | 盐野义制药株式会社 | 2020-05-12 | — | — | CN | disclosed |
| CN-110769830-A | Substituted heterocyclic compounds as allosteric modulators of group II metabotropic glutamate receptors | 马瓦隆治疗有限公司 | 2020-02-07 | — | — | CN | disclosed |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| US-20100041694-A1 | AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
| WO-2008126684-A2 | AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-23 | — | — | WO | disclosed |
| CN-100363363-C | Quinuclidine derivatives and pharmaceutical compositions containing the same | ALMIRALL PRODESFARMA SA (CH) | 2008-01-23 | — | — | CN | disclosed |
| CN-1675206-A | Quinuclidine derivatives and pharmaceutical compositions containing the same | ALMIRALL PRODESFARMA SA (CH) | 2005-09-28 | — | — | CN | disclosed |
| EP-1334092-A4 | PROCESS FOR PREPARATION OF BICYCLIC AND POLYCYCLIC MOLECULES | UNIV MONASH (AU) | 2004-08-11 | — | — | EP | disclosed |
| EP-1334092-A1 | PROCESS FOR PREPARATION OF BICYCLIC AND POLYCYCLIC MOLECULES | Monash University (AU) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002034736-A1 | PROCESS FOR PREPARATION OF BICYCLIC AND POLYCYCLIC MOLECULES | MONASH UNIVERSITY (AU) | 2002-05-02 | — | — | WO | disclosed |
| US-4883800-A | DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| US-4734419-A | Quinazoline derivatives, compositions thereof and their use in treating diabetic complications | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0218999-A2 | New quinazoline derivatives, process for their production and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041694-A1 | AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES | HDHD5, NAAA, BROX | GAA 920/4885LMNA 3240/4885ALDH1A1 3801/4885 |
| US-20110201649-A1 | AGRICULTURAL COMPOSITION | H1-0, H1-3, H1-2 | GAA 2649/4885LMNA 3681/4885ALDH1A1 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.