Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 14/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566870 | 1.00 | GRM2 (0.53) | GRM2MAOB | |
| SCHEMBL9210042 | 0.89 | GRM2 (0.52) | GRM2MAOB | |
| SCHEMBL9845306 | 0.88 | MAOA (0.51) | GRM2MAOB | |
| SCHEMBL9207719 | 0.88 | MAOA (0.51) | GRM2MAOB | |
| SCHEMBL9208901 | 0.85 | GRM2 (0.56) | GRM2 | |
| SCHEMBL9213506 | 0.84 | MAOB (0.47) | GRM2MAOB | |
| SCHEMBL9215768 | 0.84 | GRM2 (0.56) | GRM2 | |
| SCHEMBL9209386 | 0.84 | GRM2 (0.56) | GRM2 | |
| SCHEMBL9204673 | 0.84 | GRM2 (0.56) | GRM2 | |
| SCHEMBL9208087 | 0.84 | MAOB (0.48) | GRM2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |