SCHEMBL920541

SCHEMBL920541

CC/C=C/CCCOc1cccc(CNC(=O)c2cccnc2N)c1F

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
MAPK8 P45983 2/20 0.46
MET P08581 1/20 0.40
HPGD P15428 5/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RCE1 Q9Y256 1/20 0.40
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
KLKB1 P03952 1/20 0.39
CARM1 Q86X55 2/20 0.39
PRMT6 Q96LA8 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920542 1.00 LMNA (0.49) LMNAMAPK8METHPGDKDM4E
SCHEMBL922267 0.95 LMNA (0.48) LMNAMAPK8METHPGDKDM4E
SCHEMBL922268 0.95 LMNA (0.48) LMNAMAPK8METHPGDKDM4E
SCHEMBL922277 0.93 LMNA (0.47) LMNAMAPK8METHPGDKDM4E
SCHEMBL922276 0.93 LMNA (0.47) LMNAMAPK8METHPGDKDM4E
SCHEMBL920999 0.91 LMNA (0.47) LMNAMAPK8METHPGDKDM4E
SCHEMBL920998 0.91 LMNA (0.47) LMNAMAPK8METHPGDKDM4E
SCHEMBL922166 0.90 MAPK8 (0.45) LMNAMAPK8METHPGDKDM4E
SCHEMBL922164 0.90 MAPK8 (0.45) LMNAMAPK8METHPGDKDM4E
SCHEMBL921439 0.89 LMNA (0.47) LMNAMAPK8METHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 LMNA 4812/4885MAPK8 2313/4885MET 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.