SCHEMBL920559

SCHEMBL920559

Nc1ncc(Br)cc1C(=O)NCc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.50
MAPK14 Q16539 4/20 0.49
HTT P42858 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
CYP3A4 P08684 1/20 0.49
MMP13 P45452 1/20 0.49
HPGD P15428 3/20 0.49
GALR3 O60755 1/20 0.47
NR2F2 P24468 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KLKB1 P03952 1/20 0.47
KLK1 P06870 1/20 0.47
KMT2A Q03164 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
PPARG P37231 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920768 0.86 PTGER4 (0.61) MAPK8MAPK14HTTSMN1; SMN2LMNA
SCHEMBL920809 0.86 PTGER4 (0.58) MAPK8MAPK14HTTSMN1; SMN2LMNA
SCHEMBL23555768 0.82 AKR1B1 (0.50) HTTSMN1; SMN2LMNACYP3A4HPGD
SCHEMBL1585665 0.82 CNR2 (0.49) HTTSMN1; SMN2LMNAHPGDALDH1A1
SCHEMBL920461 0.81 MAPK8 (0.67) MAPK8MAPK14HTTSMN1; SMN2LMNA
SCHEMBL921448 0.79 MAPK8 (0.53) MAPK8MAPK14HTTSMN1; SMN2LMNA
SCHEMBL920265 0.79 MAPK8 (0.55) MAPK8MAPK14HTTSMN1; SMN2LMNA
SCHEMBL920665 0.78 GALR3 (0.54) MAPK8MAPK14HTTSMN1; SMN2LMNA
SCHEMBL3579623 0.76 HPGD (0.68) MAPK8MAPK14HTTSMN1; SMN2LMNA
SCHEMBL922515 0.76 HPGD (0.53) MAPK8MAPK14HTTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK8 2313/4885MAPK14 905/4885HTT 2561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.