Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | RXRG | P48443 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523934 | 0.84 | LMNA (0.64) | WDR5MAOBAOC3FKBP1ARXRA | |
| SCHEMBL29447016 | 0.84 | LMNA (0.64) | WDR5MAOBAOC3FKBP1ARXRA | |
| SCHEMBL29590819 | 0.84 | WDR5 (0.62) | WDR5MAOBAOC3FKBP1ARXRA | |
| SCHEMBL1308577 | 0.84 | WDR5 (0.62) | WDR5MAOBAOC3FKBP1ARXRA | |
| SCHEMBL9205693 | 0.82 | WDR5 (0.70) | WDR5MAOBAOC3FKBP1ARXRA | |
| SCHEMBL11280610 | 0.82 | WDR5 (0.60) | WDR5MAOBAOC3FKBP1ARXRA | |
| SCHEMBL10967871 | 0.80 | CYP3A4 (0.50) | ALDH1A1LMNAFFAR1 | |
| SCHEMBL10655455 | 0.79 | WDR5 (0.57) | WDR5MAOBAOC3FKBP1ARXRA | |
| SCHEMBL10655453 | 0.79 | WDR5 (0.57) | WDR5MAOBAOC3FKBP1ARXRA | |
| SCHEMBL8470558 | 0.79 | WDR5 (0.56) | WDR5MAOBAOC3FKBP1ARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341694-B1 | Method for production of 3-exomethylenecepham derivatives | OTSUKA KAGAKU KK (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-4958018-A | REACTING A 3-HALOMETHYL-3-CEPHEM WITH A LEAD REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0341694-A2 | Method for production of 3-exomethylenecepham derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1989-11-15 | — | — | EP | disclosed |
| US-4031084-A | Process for cephalosporin antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | disclosed |