Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | PPARD | Q03181 | 2/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | WDR5 | P61964 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447016 | 1.00 | LMNA (0.64) | LMNAPPARGPPARDFFAR1ALOX15 | |
| SCHEMBL413254 | 0.86 | LMNA (0.81) | LMNAPPARGFFAR1ALOX15KDM4E | |
| SCHEMBL1308577 | 0.85 | WDR5 (0.62) | LMNAPPARGPPARDFFAR1WDR5 | |
| SCHEMBL29590819 | 0.85 | WDR5 (0.62) | LMNAPPARGPPARDFFAR1WDR5 | |
| Chlorobenzene SCHEMBL7068183 | 0.85 | ALOX15 (0.80) | LMNAPPARGPPARDFFAR1ALOX15 | |
| SCHEMBL9205693 | 0.84 | WDR5 (0.70) | LMNAPPARGPPARDFFAR1WDR5 | |
| SCHEMBL11280610 | 0.84 | WDR5 (0.60) | LMNAPPARGPPARDWDR5RXRA | |
| SCHEMBL9205686 | 0.84 | WDR5 (0.65) | LMNAPPARGPPARDFFAR1WDR5 | |
| SCHEMBL11076031 | 0.83 | WDR5 (0.55) | PPARGPPARDFFAR1WDR5RXRA | |
| SCHEMBL9786924 | 0.83 | MAPT (0.61) | LMNAWDR5RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| EP-4099814-A1 | METHOD FOR IMPROVING THE STABILITY OF A CULTIVATED PLANT | Omnicult Farmconcept GmbH (DE) | 2022-12-14 | — | — | EP | claimed |
| WO-2021156169-A1 | METHOD FOR IMPROVING THE STABILITY OF A CULTIVATED PLANT | OMNICULT FARMCONCEPT GMBH (DE) | 2021-08-12 | — | — | WO | claimed |
| CN-110724115-A | Method for preparing 2-amino-5-substituted-1, 3, 4-thiadiazole | 陕西科技大学 | 2020-01-24 | — | — | CN | claimed |
| US-8883685-B2 | Nitrogen containing isethionic acid salt in registerable, stable agricultural formulations | HUNTSMAN PETROCHEMICAL LLC (US) | 2014-11-11 | — | — | US | claimed |
| EP-2113502-B1 | Hydrazyde type compounds and the use thereof in pharmaceutical compositions for the treatment of cardiovascular diseases | CLINIGENETICS (FR) | 2012-11-14 | — | — | EP | claimed |
| CN-102516196-A | Alpha, beta-unsaturated ketone compound containing thiazole heterocycle, its preparation method and application | UNIV SHANDONG | 2012-06-27 | — | — | CN | claimed |
| US-8158809-B2 | Podophyllotoxin derivatives | SUTTER WEST BAY HOSPITALS (US) | 2012-04-17 | — | — | US | claimed |
| US-20090298870-A1 | PODOPHYLLOTOXIN DERIVATIVES | Sutter West Bay Hospitals, dba California Pacific Medical Center and Catholic Healthcare West | 2009-12-03 | — | — | US | claimed |
| US-20080108115-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | DFB BIOTECH, INCORPORATED (US) | 2008-05-08 | — | — | US | claimed |
| EP-0954596-B1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON INC (US) | 2006-01-04 | — | — | EP | claimed |
| EP-1538214-A1 | Enhanced production of taxanes by cell cultures of taxus species | PHYTON, INC. (US) | 2005-06-08 | — | — | EP | claimed |
| US-6289286-B1 | Surface regeneration of biosensors and characterization of biomolecules associated therewith | BIACORE AB (SE) | 2001-09-11 | — | — | US | claimed |
| EP-1082607-A1 | SURFACE REGENERATION OF BIOSENSORS | Biacore AB (SE) | 2001-03-14 | — | — | EP | claimed |
| WO-1999063333-A1 | SURFACE REGENERATION OF BIOSENSORS | BIACORE AB (SE) | 1999-12-09 | — | — | WO | claimed |
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | claimed |
| EP-0522906-B1 | Herbicidal wettable powders and methods of preparation | FRANCAIS PROD IND CFPI (FR) | 1998-08-19 | — | — | EP | claimed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | claimed |
| US-5374607-A | Filler particles constitute support or carrier for active substance | C F P I (FR) | 1994-12-20 | — | — | US | claimed |
| US-4946761-A | POLYMER CONTAINING CARBOXYL END GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298870-A1 | PODOPHYLLOTOXIN DERIVATIVES | APEH, DAGLA, DPY30 | LMNA 1033/4885PPARG 958/4885PPARD 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.