Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204754 | 0.92 | LMNA (0.44) | BCHETSHRTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9200646 | 0.87 | ELANE (0.39) | TSHRTDP1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9203895 | 0.87 | MEN1 (0.51) | SMN1; SMN2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL9202975 | 0.85 | CYP2D6 (0.39) | SMN1; SMN2ALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL9206463 | 0.84 | CACNA1B (0.39) | TSHRSMN1; SMN2ALDH1A1HPGDACHE | |
| SCHEMBL27946955 | 0.84 | CES2 (0.50) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10497654 | 0.83 | CES2 (0.51) | TSHRTDP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL9197566 | 0.83 | MAPT (0.35) | TSHRSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL9207327 | 0.80 | ALDH1A1 (0.45) | TDP1L3MBTL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5078093 | 0.80 | TDP1 (0.51) | TSHRTDP1L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |