Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199373 | 0.81 | F7 (0.45) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11370901 | 0.81 | ALDH1A1 (0.47) | HTTALDH1A1CYP1A2SMN1; SMN2 | |
| Charcoal, Activated SCHEMBL10444782 | 0.79 | TBXAS1 (0.55) | TBXA2RTBXAS1 | |
| SCHEMBL10444781 | 0.79 | TBXAS1 (0.55) | TBXA2RTBXAS1 | |
| SCHEMBL8883856 | 0.79 | TBXAS1 (0.68) | TBXA2RTBXAS1 | |
| Bicarbonate SCHEMBL9208564 | 0.79 | TBXAS1 (0.57) | TBXA2RTBXAS1 | |
| SCHEMBL8883848 | 0.79 | TBXAS1 (0.68) | TBXA2RTBXAS1 | |
| SCHEMBL9210620 | 0.78 | TBXA2R (0.56) | HDAC8ALDH1A1TBXA2RTBXAS1CYP1A2 | |
| SCHEMBL9208561 | 0.78 | TBXAS1 (0.65) | TBXA2RTBXAS1 | |
| SCHEMBL8885287 | 0.78 | TBXAS1 (0.65) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397044-B1 | Arylsulfonamides, medicines containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1995-12-27 | — | — | EP | disclosed |
| EP-0397044-A2 | Arylsulfonamides, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-11-14 | — | — | EP | disclosed |