Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209889 | 0.90 | PPARA (0.44) | PPARACYP2D6NR1I2CYP3A4THRA | |
| SCHEMBL9202726 | 0.87 | CYP2D6 (0.51) | PPARACYP2D6NR1I2CYP3A4THRA | |
| SCHEMBL9207015 | 0.86 | NR1I2 (0.43) | PPARACYP2D6NR1I2CYP3A4THRA | |
| SCHEMBL9844935 | 0.85 | PPARA (0.37) | PPARACYP2D6NR1I2CYP3A4THRA | |
| SCHEMBL9203609 | 0.84 | PPARA (0.38) | PPARACYP2D6NR1I2CYP3A4THRA | |
| SCHEMBL9201165 | 0.82 | CYP2D6 (0.56) | CYP2D6NR1I2CYP3A4THRATHRB | |
| SCHEMBL9205000 | 0.81 | NR1I2 (0.38) | PPARACYP2D6NR1I2CYP3A4MEN1 | |
| SCHEMBL9201720 | 0.80 | CYP3A4 (0.52) | PPARACYP2D6NR1I2CYP3A4MEN1 | |
| SCHEMBL9207040 | 0.78 | NR1I2 (0.44) | PPARACYP2D6NR1I2CYP3A4 | |
| SCHEMBL9201818 | 0.77 | NR1I2 (0.39) | PPARACYP2D6NR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5175178-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4942241-A | PICORNAVIRUS INCLUDING RHINOVIRUS | STERLING DRUG INC. (US) | 1990-07-17 | — | — | US | disclosed |