Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206575 | 0.85 | PPARA (0.41) | PPARATHRATHRBCYP2D6NR1I2 | |
| SCHEMBL9209889 | 0.84 | PPARA (0.44) | PPARATHRATHRBCYP2D6NR1I2 | |
| SCHEMBL9203609 | 0.81 | PPARA (0.38) | PPARATHRATHRBCYP2D6NR1I2 | |
| SCHEMBL9205000 | 0.76 | NR1I2 (0.38) | PPARACYP2D6NR1I2CYP3A4MEN1 | |
| SCHEMBL9201720 | 0.75 | CYP3A4 (0.52) | PPARACYP2D6NR1I2CYP3A4KDM4E | |
| SCHEMBL9207040 | 0.73 | NR1I2 (0.44) | PPARACYP2D6NR1I2CYP3A4 | |
| SCHEMBL9202726 | 0.73 | CYP2D6 (0.51) | PPARATHRATHRBCYP2D6NR1I2 | |
| SCHEMBL9201818 | 0.72 | NR1I2 (0.39) | PPARACYP2D6NR1I2CYP3A4 | |
| SCHEMBL9207015 | 0.72 | NR1I2 (0.43) | PPARATHRATHRBCYP2D6NR1I2 | |
| SCHEMBL5089005 | 0.70 | NR1I2 (0.45) | PPARACYP2D6NR1I2CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |