⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509562 | 0.69 | CA1 (0.31) | — | |
| SCHEMBL6228672 | 0.67 | — | — | |
| SCHEMBL14281828 | 0.67 | GAA (0.30) | — | |
| SCHEMBL3020239 | 0.67 | — | — | |
| SCHEMBL10367224 | 0.67 | — | — | |
| SCHEMBL35212134 | 0.64 | HTR2C (0.30) | — | |
| SCHEMBL10551325 | 0.63 | ADAMTS4 (0.30) | — | |
| SCHEMBL24329390 | 0.62 | — | — | |
| SCHEMBL9128747 | 0.62 | HTR1A (0.42) | — | |
| SCHEMBL3975448 | 0.62 | HTR3A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642508-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0627434-A1 | Tricyclic quinoxalinedione derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4499270-A | INHIBITING THE GROWTH OF MICROORGANISMS | RIKER LABORATORIES, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4348521-A | BACTERICIDES, FUNGICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-09-07 | — | — | US | disclosed |