Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MARS1 | P56192 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205210 | 0.92 | CHRNA7 (0.54) | CHRNA7CA9FAAHTHRBALDH1A1 | |
| SCHEMBL9200872 | 0.86 | CHRNA7 (0.71) | CHRNA7CA9FAAHTHRBPTGS2 | |
| SCHEMBL9202688 | 0.86 | CHRNA7 (0.71) | CHRNA7CA9FAAHTHRBPTGS2 | |
| SCHEMBL9205261 | 0.85 | CHRNA7 (0.52) | CHRNA7CA9FAAHTHRBALDH1A1 | |
| SCHEMBL9200861 | 0.84 | SCN9A (0.45) | CHRNA7ALDH1A1HPGDMARS1PTGS2 | |
| SCHEMBL9206649 | 0.84 | CHRNA7 (0.56) | CHRNA7CA9FAAHTHRBPTGS2 | |
| SCHEMBL9201863 | 0.80 | PDE4B (0.51) | CHRNA7CA9FAAHALDH1A1HPGD | |
| SCHEMBL9201539 | 0.80 | CA9 (0.70) | CHRNA7CA9FAAHPTGS2MAPT | |
| SCHEMBL9206389 | 0.80 | CA9 (0.64) | CHRNA7CA9FAAHTP53MAPT | |
| SCHEMBL2837904 | 0.79 | THRB (0.47) | CHRNA7THRBALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418845-B1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-09 | — | — | EP | disclosed |