Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 7/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12748474 | 0.78 | HTT (0.36) | GAAALDH1A1PKMKCNE1KCNQ1 | |
| SCHEMBL12748471 | 0.78 | HTT (0.36) | GAAALDH1A1PKMKCNE1KCNQ1 | |
| SCHEMBL12748473 | 0.78 | HTT (0.36) | GAAALDH1A1PKMKCNE1KCNQ1 | |
| SCHEMBL9201086 | 0.77 | TLR3 (0.47) | ABCC9GAAALDH1A1PKMMAPT | |
| SCHEMBL9200591 | 0.76 | ABCC9 (0.39) | ABCC9HTR6KDM4EGAAHPGD | |
| SCHEMBL9206721 | 0.74 | KDM4E (0.44) | ABCC9KDM4EKCNE1KCNQ1 | |
| SCHEMBL9207155 | 0.72 | CTSD (0.39) | KCNE1KCNQ1 | |
| SCHEMBL9205841 | 0.71 | ABCC9 (0.54) | ABCC9HTR6KCNA5KCNE1KCNQ1 | |
| SCHEMBL9869923 | 0.71 | ABCC9 (0.52) | ABCC9HTR6KCNA5ALDH1A1MAPT | |
| SCHEMBL9200860 | 0.71 | ABCC9 (0.54) | ABCC9HTR6KCNA5KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514935-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-11-08 | — | — | EP | disclosed |
| US-5236935-A | Hypotensive agents | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-08-17 | — | — | US | disclosed |
| EP-0514935-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |