Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302707 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL303118 | 1.00 | — | — | |
| SCHEMBL9219931 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL577753 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL2564589 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL3386412 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL2565171 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL304992 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL577732 | 1.00 | TSHR (0.53) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL59455 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004306-A1 | ORGANIC CHARGE TRANSFER COMPOUNDS WITH LIQUID CRYSTAL PROPERTIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-02-09 | — | — | WO | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |