SCHEMBL9207772

SCHEMBL9207772

CCCCNc1nc(NC(CCC)C2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)nc(NC(CCC)C2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)n1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADAMTS5 Q9UNA0 1/20 0.33
HRH4 Q9H3N8 1/20 0.31
MERTK Q12866 4/20 0.31
FLT3 P36888 2/20 0.31
TYRO3 Q06418 2/20 0.31
GAS6 Q14393 2/20 0.31
EHMT2 Q96KQ7 1/20 0.30
EHMT1 Q9H9B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231052 0.92 IDH1 (0.31)
SCHEMBL9428557 0.92 KMT2A (0.37) HRH4
SCHEMBL9429082 0.92 KMT2A (0.37)
SCHEMBL9428468 0.92 HTR7 (0.33)
SCHEMBL78005 0.91 CDK1 (0.33) HRH4
SCHEMBL9428294 0.91 FLT3 (0.32) MERTKFLT3TYRO3GAS6EHMT2
SCHEMBL9427998 0.88 FFAR4 (0.32) MERTKFLT3TYRO3GAS6
SCHEMBL9429157 0.88 KDM4E (0.34)
SCHEMBL9428450 0.88 KMT2A (0.37)
SCHEMBL9428559 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed